Day 25, update. Upward trending :) and do worms dream?

It’s been just about 25 days since I inoculated.

Side effects are non existent. Even the vague nausea that I was feeling a week or so ago, I cant even attribute to the little guys, because I was a bit anxious about “day 12/13” (when they molt & migrate) side effects, and we’ve had an unbelievable heat wave in New England, and I have no A/C, and its been above 90 F almost everyday.

I have to say, nothing but good news on the bowel front. I think my little comrades must be nicely settled in by now, and have been slowly working their “magic,” as I’ve had solid bowel movements every single day for the last 6 or 7 days. Only 1-2 bowel movements per day. The only time I’ve been able to have consistent solid bowel movements (with no mucus or other markers of inflammation) has been when I’ve gone on a full blown prednisone regimen for a month or so. While I have achieved periods of “remission” on my normal IBD drug, Colazal (a 5-ASA), I’ve still never been able to get solid stools for more than a day or so without prednisone, and have always had some trace of mucus. I’m not on prednisone at all, but still taking Colazal, but only 500mg, down from 750mg which has been my daily dose for 5+ years. This is all encouraging but I’m very wary of pulling a G Bush and throwing up a “Mission Accomplished” banner.

*An important note here. Most people with autoimmune diseases who are interested in helminthic therapy will most likely be using Necator americanus, or human hookworm, as their worm of choice, however as mentioned elsewhere, this blog is about Trichuris trichiura, or human whipworm, which is a (seemingly) better organism for specifically Ulcerative Colitis. In any case, not to beat to this distinction to death, but my reason for bringing this up again is to point out that the effects of human whipworm begin to be felt FAR sooner than with hookworm. With whipworm, as far as I have learned from research and speaking with others, the effects begin within weeks, while hookworm the effects begin within months, often taking up to three or six months. For some conditions, the ‘full effect’ from hookworm may even take up to a year. Patience, not something we are used to in the instant gratification world of pharmacological medicine, is a virtue here.

From my reading of a little parasitology online, human whipworm take about 30 days from inoculation to maturity. After day 30, I will begin to have a better idea of what I can expect from this therapy. After two months, I expect to have an even more solid idea.

So it goes.

Oh, and just in case some of you out there are curious if I can “feel” them (I know I was, even when told otherwise by smarter minds), my answer is no, not at all. I dont think about them nearly as much as I imagined either. In fact as time goes on, I mostly forget that I’ve “got worms.” Once, I did say goodnight and wish them sweet dreams, just because I’m a bit weird. What would a little bowel parasite dream of, anyhow? A never ending colon? A young and nicely curved female whipworm perhaps?

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14 responses

  1. Alli

    Just wanted to let you know you’ve got a reader here. I’ve got UC – and the “remission” you describe sounds just like mine.

    Wishing you good luck with this experiment and watching with interest!

    July 16, 2010 at 11:57 am

    • Hi Alli! and thanks

      July 16, 2010 at 8:31 pm

  2. THis is excellent, Mike! I wish I could get access to whipworm as I could use some solid bowel movements without mucus!

    July 16, 2010 at 1:56 pm

  3. MG

    great news. keep your updates coming.

    July 16, 2010 at 4:51 pm

  4. Thanks all! yes it’s encouraging, but really its far too early to have any idea about benefits, especially long term.

    The journey continues..

    July 16, 2010 at 6:45 pm

  5. Marc

    The only question is that when you wished them goodnight did they answer???

    All sounds good Mike, good luck for the next month, hoping there is obvious improvement over the next few weeks.

    July 18, 2010 at 3:53 pm

    • heheh.

      Thanks Marc, I’ll keep you updated. *fingers crossed*

      July 18, 2010 at 4:33 pm

  6. MG

    do you know your current vitamin D levels? Are they in the 50ng/ml-80ng/ml range?

    July 18, 2010 at 4:45 pm

    • I dont actually. What are your thoughts on Vit D? I might try to do a blood test soon with doc, maybe he can check that.

      July 18, 2010 at 5:43 pm

  7. HS

    I highly recommend you get tested. Read this: http://www.sciencedaily.com/releases/2010/01/100127104904.htm
    You want to be in the 50ng/ml-80ng/ml range – it should help you with UC.

    July 20, 2010 at 7:47 am

    • great article, thanks. it sounds like Vit D is a really important part of the equation, I have been tested before, but dont know what range I was in. Next time I do blood work I’ll check

      July 22, 2010 at 8:18 pm

  8. HS

    you can even get tested yourself for $65 at http://www.zrtlab.com/vitamindcouncil

    July 20, 2010 at 3:01 pm

  9. Nancy

    Mike,

    Love your blog–especially the “bowel of love” cartoon. Keep us posted on your progress!

    Have a few questions that I’d like to ask you “offline.” Would you mind?

    July 21, 2010 at 4:44 pm

    • Hi Nancy, hehe thanks, yes the “bowel of love” was a perfect find for this blog.

      I’d be happy to try to answer any questions you have ‘offline,’ you can reach me through email at

      colon.comrades@gmail.com

      July 22, 2010 at 7:54 pm

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